Emodin glucoside B
Emodin-8-glucoside
CAS: 23313-21-5
Molecular Formula: C21H20O10
Emodin glucoside B - Names and Identifiers
Emodin glucoside B - Physico-chemical Properties
| Molecular Formula | C21H20O10 |
| Molar Mass | 432.38 |
| Density | 1.667±0.06 g/cm3(Predicted) |
| Melting Point | 219-220 °C |
| Boling Point | 798.7±60.0 °C(Predicted) |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents. |
| Appearance | Yellow powder |
| Color | Yellow to Brown |
| pKa | 6.27±0.20(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| MDL | MFCD01725365 |
| Physical and Chemical Properties | Light yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dry roots and rhizomes of Polygonum multiflorum, Polygonaceae plant palm leaf rhubarb. |
Emodin glucoside B - Risk and Safety
| HS Code | 29389090 |
Emodin glucoside B - Reference
| Reference Show more | 1. Luo Yiyuan, Liu, Juan, Liu, Ting, et al. Simultaneous determination of stilbene anthraquinone flavonoids and phenolic acids in Polygonum multiflorum by UPLC-MS/MS [J]. Journal of Mass Spectrometry 2016(4):327-335. 2. Hou Wen, Shi Yanhong, Song Min, et al. Simultaneous determination of four anthraquinones in Polygonum multiflorum Thunb. By one-Test multi-evaluation method [J]. Chinese Journal of Traditional Chinese Medicine, 2020 v.45(01):141-149. 3. Zhang Yu, fan, Wang Lei, Wang Xin, et al. Identification of radix polygoni multiflori with different processing time and methods by TLC [J]. Chinese Journal of Traditional Chinese Medicine 2018 v.33(11):408-411. 4. Wang, Jing, Yue, Zhang, fan, Chai, Chong, et al. Correlation between the color of Polygonum multiflorum Thunb and the contents of anthraquinones and stilbene glycoside [J]. Central South pharmacy 2020(4). 5. Luo Yiyuan, Liu Juan, Liu Xunhong, etc. Analysis of chemical constituents in Polygonum multiflorum Thunb and Polygonum multiflorum Thunb. From the same origin [J]. Natural Product Research and Development 2016 28(7):1035-1044. 6. Wang Qi, Zhang Qianyan, Wen Hairuo, etc. Potential hepatotoxicity of main monomers of Polygonum multiflorum Thunb. Based on liver micro-tissue [J]. Chinese Journal of Traditional Chinese Medicine, 2020, v.45(12):236-241. 7. Min, Zhang Zhi, Li hearing, Tao Cai Xia, Jia Ping, Wang Guangzhong. Comparative study on HPLC fingerprint of rhubarb before and after preparation [J]. Shi Zhen, National Medicine, 2020,31(06):1361-1364. 8. Wu Yuyan, Ren huixu, Feng Youlong, Zhang Li, Zhang Changlin. Study on HPLC fingerprint and content determination of three components of Anshen Bunao capsules [J]. Journal of Guangdong Pharmaceutical University, 2020,36(06):778-783. 9. Wang Yingshu, Zhu Guangyan, Wang Bing, Li Jierong, Li Qianfei, He Xiaoyan, Zhao Jiayi, xiaoyanfeng. Effects of conventionally steaming and pharmacopoeia continuous steaming of black bean juice on contents of 12 components in Polygonum multiflorum [J]. Chinese herbal medicine, 2020,51(19):4972-4982. 10. Lin, Longfei, et al. "Application of iTRAQ-based quantitative proteomics approach to identify deregulated proteins associated with liver toxicity induced by polygonum multiflorum in rats." Cellular Physiology and Biochemistry 43.5 (2017): 2102-2116.https:/ 11. Lin, Longfei et al. “A New Perspective on Liver Injury by Traditional Chinese Herbs Such As Polygonum multiflorum: The Geographical Area of Harvest As an Important Contributory Factor." Frontiers in pharmacology vol. 8 349. 20 Jun. 2017, doi:10.3389/fphar. 12. Lin, Longfei, et al. "Hepatotoxicity and mechanism study of chrysophanol-8-O-glucoside in vitro." Biomedicine & Pharmacotherapy 120 (2019): 109531.https://doi.org/10.1016/j.biopha.2019.109531 13. [IF=10.588] Longfei Lin et al."A novel method to analyze hepatotoxic components in Polygonum multiflorum using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry."J Hazard Mater. 2015 Dec;299:249 14. [IF=5.81] Zhang Miao et al."Interpretation the Hepatotoxicity Based on Pharmacokinetics Investigated Through Oral Administrated Different Extraction Parts of Polygonum multiflorum on Rats."Front Pharmacol. 2018 May;0:505 15. [IF=5.81] Lin Longfei et al."A New Perspective on Liver Injury by Traditional Chinese Herbs Such As Polygonum multiflorum: The Geographical Area of Harvest As an Important Contributory Factor."Front Pharmacol. 2017 Jun;0:349 16. [IF=5.645] Fangyuan Gao et al."Cyclodextrin-based ultrasonic-assisted microwave extraction and HPLC-PDA-ESI-ITMSn separation and identification of hydrophilic and hydrophobic components of Polygonum cuspidatum: A green rapid and effective process."Ind Crop Prod. 20 17. [IF=4.379] Wang Qi et al."Identification and characterization of the structure-activity relationships involved in UGT1A1 inhibition by anthraquinone and dianthrone constituents of Polygonum multiflorum."Sci Rep-Uk. 2017 Dec;7(1):1-9 18. [IF=3] Juan HUANG et al."Chemical profiles and metabolite study of raw and processed Polygoni Multiflori Radix in rats by UPLC-LTQ-Orbitrap MSn spectrometry."Chin J Nat Medicines. 2018 May;16:375 19. [IF=1.902] Longfei Lin et al."Simultaneous determination of 14 constituents of Radix polygoni multiflori from different geographical areas by liquid chromatography-tandem mass spectrometry."Biomed Chromatogr. 2015 Jul;29(7):1048-1055 20. [IF=1.902] Longfei Lin et al."Characterization of the constituents in rat plasma after oral administration of radix polygoni multiflori extracts by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry."Biomed Chromatogr. 2015 Oct;29(10 21. [IF=0] Longfei Lin et al."Application of iTRAQ-Based Quantitative Proteomics Approach to Identify Deregulated Proteins Associated with Liver Toxicity Induced by Polygonum Multiflorum in Rats."Cell Physiol Biochem. 2017;43(5):2102-2116 22. [IF=4.142] Wang Chenxi et al."Systematic quality evaluation of Peiyuan Tongnao capsule by offline two-dimensional liquid chromatography/quadrupole-Orbitrap mass spectrometry and adjusted parallel reaction monitoring of quality markers."Anal Bioanal Chem. 2019 Nov;4 23. [IF=3.935] Yanchao Xing et al."An effective strategy for distinguishing the processing degree of Polygonum multiflorum based on the analysis of substance and taste by LC-MS ICP-OES and electronic tongue."J Pharmaceut Biomed. 2021 Oct;205:114328 24. [IF=3.743] Longfei Lin et al."Hepatotoxicity and mechanism study of chrysophanol-8-O-glucoside in vitro."Biomed Pharmacother. 2019 Dec;120:109531 25. [IF=5.645] Huilan Yue et al."Hypoglycemic ingredients identification of Rheum tanguticum Maxim. ex Balf. by UHPLC-triple-TOF-MS/MS and interrelationships between ingredients content and glycosidase inhibitory activities."Ind Crop Prod. 2022 Apr;178:114595 26. [IF=5.811] Kong Wei-Song et al."Beware of the Potential Risks for Polygoni Multiflori Caulis-Induced Liver Injury."Front Pharmacol. 2022 Apr;0:928 |
Emodin glucoside B - Introduction
Nature:
1. It is a white to light yellow crystalline powder that is easily soluble in hot water and ethanol, slightly soluble in ethanol and ether, and almost insoluble in ethyl acetate.
2. It has pharmacological activities such as anti-inflammatory, antibacterial, and anti-tumor properties.
Method:
Mainly extracted from emodin or rhubarb extract. A typical preparation method is to use column chromatography technology for separation and purification.
Security information:
1. Avoid contact with skin and inhalation of powder.
2. It needs to be stored in a sealed container, avoiding direct sunlight.
Last Update：2024-06-06 11:02:29
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